Praise for 
Estrogen Matters:




"I hope Estrogen Matters draws enough attention to counter the fears and misinformation about HRT that so many women, and their physicians, still hold." ― Phyllis Greenberger, MSW, former President and CEO of the Society for Women's Health Research

“Well written, insightful, and hard hitting, Estrogen Matters successfully rebuts the billion-dollar, government-led study known as the Women’s Health Initiative, which claimed that hormones for post-menopausal women are harmful. That study was wrong. It turns out estrogens do matter for women’s health.”—Vincent T. DeVita Jr., MD, Professor of Medicine, Yale School of Public Health and Yale Cancer Center

“If you’re one of the many menopausal women who avoid HRT to treat your symptoms because of all the scary headlines, this book is a must-read.”— Jennifer Ouellette, author of Me, Myself and Why


More praise ︎



About the Authors



AVRUM BLUMING, MD
Avrum Bluming received his MD from the Columbia College of Physicians and Surgeons. He spent four years as a senior investigator for the National Cancer Institute and for two of those years was director of the Lymphoma Treatment Center in Kampala, Uganda. He organized the first study of lumpectomy for the treatment of breast cancer in Southern California in 1978, and for more than two decades he has been studying the benefits and risks of hormone replacement therapy administered to women with a history of breast cancer. Dr. Bluming has served as a clinical professor of medicine at USC and has been an invited speaker at the Royal College of Physicians in London and the Pasteur Institute in Paris. He was elected to mastership in the American College of Physicians, an honor accorded to only five hundred of the over one hundred thousand board-certified internists in this country.

CAROL TAVRIS, PhD

Carol Tavris received her PhD in social psychology from the University of Michigan. Her books include Mistakes Were Made (But Not by Me), with Elliot Aronson; Anger: The Misunderstood Emotion, and The Mismeasure of Woman. She has written articles, op-eds, and book reviews on topics in psychological science for a wide array of publications — including the Los Angeles Times, the New York Times Book Review, the Wall Street Journal, and the TLS — and a column, “The Gadfly,” for Skeptic magazine. She is a fellow of the Association for Psychological Science and has received numerous awards for her efforts to promote gender equality, science, and skepticism.




Available in hardcover, ebook, and audio

UK edition, Oestrogen Matters
German edition, Öestrogen!



AMAZON (US
AMAZON (UK)
BARNES & NOBLE
INDIEBOUND
iBOOKS
LITTLE, BROWN

HACHETTE / AUSTRALIA

 

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Research
Updates




September 2019
Much Ado About Little: More False Alarms from
Lancet

In September, 2019, the British journal Lancet published a paper claiming, once again, that Hormone Replacement Therapy (HRT)—also called Menopausal Hormone Therapy (MHT)—increases the risk of breast cancer. Naturally, this article generated more headlines designed to frighten women away from hormones rather than guide them to an informed decision. And once again, a close reading of the study reveals that the data do not support the alarm.

For a  summary of our objections, see:
https://www.dropbox.com/s/7nehxo0b14gfnm1/Lancet_website_update_091519.pdf?dl=0


Update: Brain
Medications to Prevent Alzheimer’s:
Does anything work?

Very often the news reports another effort to find a pill that might prevent Alzheimer’s disease; sadly, none of these efforts to date has been effective. For example, because the deposition of amyloid in the brain is a diagnostic sign of Alzheimer’s Disease, researchers have experimented with verubecestat, a pill that blocks production of beta-amyloid. However, when administered to people with some memory impairment and elevated brain amyloid levels, who did not have clinically defined dementia, it failed to prevent progression to Alzheimer’s disease during a 104-week trial in which 1,454 patients had been enrolled. (Egan MF, Kost J, Voss T, et al. Randomized trial of verubecestat for prodromal Alzheimer’s disease. New England Journal of Medicine April, 2019;380:1408-20)


Update on Bioidentical Hormones


Many women are interested in bioidentical hormones, an issue that causes great confusion. Regulated bioidentical hormones are FDA approved and marketed by commercial pharmaceutical companies. But bioidenticals made by compounding pharmacies are completely unregulated by the FDA, and can contain useless or even harmful ingredients.

We urge women who are confused about bioidenticals to read further.

We recommend this superb review by Cathryn Jakobson Ramin:
http://www.menopause.org/docs/default-source/professional/the-hormone-hoax-thousands-fall-for-oct-2013-more.pdf

For readers who want the evidence as presented by medical professionals, we recommend these articles.


Pregnancy after Breast Cancer: Is It Safe For Survivors?

The answer is yes.  At the annual meeting of the American Society of Clinical Oncology in June, 2019, an international team of investigators reported a retrospective, case-control study of 1,252 women who had been diagnosed with breast cancer, all of whom had BRCA gene mutations. Of this group, 16% (195) eventually became pregnant and were followed over the next decade.  The women who became pregnant had a longer disease-free survival than women who did not become pregnant, although both groups were matched for age, tumor size, nodal status, hormone receptor status, type of surgery, and type of endocrine therapy.  The two groups did not differ in overall survival either. Interestingly, but not surprisingly, hormone receptor status of the tumor did not affect disease-free survival or overall survival among the pregnant patients.

This study provides further evidence that pregnancy, which elevates levels of estrogen tenfold, does not fuel its recurrence.

See: Lambertini M et al.
https://www.ncbi.nlm.nih.gov/pubmed/29087485


January 31, 2019:
The Los Angeles Times 

The Los Angeles Times runs a featured opinion essay based on Estrogen Matters.  See:

https://www.latimes.com/opinion/op-ed/la-oe-bluming-tavris-hormone-replacement-therapy-20190131-story.html


HRT Recent Reports

Readers interested in updated research pertaining to topics in the book—including the failure of calcium and vitamin D supplements to prevent hip fracture; the benefits of HRT on the heart and in preventing dementia; the safety of HRT for women who have the BRCA1 genetic mutation and had their ovaries removed to prevent ovarian cancer; and the risks of Neurotin for menopausal symptoms—can find the evidence here:

https://www.dropbox.com/s/6gk4pil6o1plxt2/HRT_recent_reports_011219.pdf?dl=0


December 18, 2018:
HRT and Risk of Breast Cancer

In yet another blow against the conclusions of the WHI, Howard Hodis at USC and Phillip Sarrel at Yale point out that in all the WHI papers studying breast cancer, the risk of breast cancer among women randomized to estrogen alone (consistently reported as showing no increased risk) was the same as the risk of breast cancer among women randomized to the combination of estrogen and progestin (HRT) (reported as showing an increased risk in some papers). The different conclusion was due to the low risk noted in the HRT control group (randomized to placebo). When these HRT treated subjects are compared to the placebo control subjects from the estrogen only study, no increase in risk is noted. 

We urge interested readers and physicians to read this important paper.

https://www.tandfonline.com/doi/full/10.1080/13697137.2018.1514008


September 4, 2018:
The London Times

Hormone therapy: why everything you thought you knew about HRT is wrong.

https://www.dropbox.com/s/jwvm3dzugcmzfml/TimesOM.pdf?dl=0





Podcasts
& Lectures




February 26, 2019:
Podcast with Dr. Peter Attia


Dr. Peter Attia, a Stanford/Johns Hopkins/NIH-trained physician, hosts long-form (“ultra-deep-dive") conversations with researchers on new and important directions in medicine. The Peter Attia Drive Podcast is a weekly podcast focusing on health, longevity, well-being, and critical thinking in science. Avrum and Carol spoke at length.

You can download podcast #42 here:

https://itunes.apple.com/us/podcast/42-carol-tavris-ph-d-avrum-bluming-m-d-controversial/id1400828889?i=1000430560132&mt=2


April 12, 2019:
Podcast with Jill Angelo and Dr. Rebecca Dunsmoor-Su

A 40-minute podcast with Jill Angelo, CEO of genneve, a website devoted to providing women in menopause with the best information available (https://genneve.com), and Dr. Rebecca Dunsmoor-Su, an ob-gyn and epidemiologist.

You can find the podcast and genneve’s accompanying blog at:
https://genneve.com/menopause-whi-breast-cancer/


August 16, 2019:
Podcast with Amanda Thebe, “Over 40 Fitness”


You can find the podcast and Amanda’s accompanying blog at:
https://www.fitnchips.com/2019/08/estrogen-matters-with-avrum-bluming-and-carol-tavris/


May 20, 2019:
Podcast with Jim Underdown, Executive Director, Center for Inquiry West

The Center for Inquiry focuses on promoting science and skepticism—examining the evidence for ideas that are outdated, harmful, or wrong.

You can find the podcast at:
https://pointofinquiry.org/2019/05/carol-tavris-avrum-bluming-estrogen-and-breast-cancer/


May 6, 2019:

Interview with Dr. Chris Duff of FundRx

FundRx Venture Partner Perspectives was created to share the knowledge and opinions of a diverse array of healthcare clinical and industry experts. In this extended conversation, Avrum and Carol discuss Estrogen Matters and updates since the book’s publication.

https://medium.com/@fund_rx/venture-partner-perspectives-dr-avrum-bluming-dr-carol-tavris-41ca3b4076b6


April 23, 2019:
Podcast with Danny Lennon


Danny Lennon is founder of Sigma Nutrition Radio, which conducts weekly interviews with researchers on topics that apply to evidence-based practice in health and nutrition.  

https://sigmanutrition.com/podcasts/


January 10, 2019:
Dr. Barb (MiddlesexMD) Podcast


Avrum and Carol did a featured podcast on Dr. Barb (DePree’s) MiddlesexMD website, “the fullness of midlife.”  Dr. Barb, an ob-gyn, has been an enthusiastic supporter of Estrogen Matters and begins the conversation saying, "This book is exactly what I needed to read, and I am so thrilled someone took on this project.”

You can read a transcript or listen to the conversation here:
https://middlesexmd.com/blogs/the-fullness-of-midlife/podcast-risk-versus-benefit


June 8, 2019:
Dr. Tavris gave a keynote address on Estrogen Matters to the Society for Menstrual Cycle Research, Colorado Springs, Co.


November 3, 2018:
Dr. Bluming spoke at the 9th Annual Symposium of The Miami Center for Obstetrics, Gynecology, & Human Sexuality in Miami, Florida.


October 31, 2018:
An international women’s health conference, organized by the European Breast Cancer Coalition, the Surgical Interventional Trials Unit at University College London (UCL), Pink Ribbon, and a popular website directed toward health issues for women in their 40s, examined how women are often denied the information they need to make a shared decision with their doctors regarding their own health needs. Dr. Bluming was a featured speaker, as described in a guest post by Dr. Louise Newson.


October 31, 2018:
Dr. Bluming spoke at a Breast Cancer Symposium, entitled: Breast Cancer Treatment - Doctor’s Dilemma or Patient’s Choice?